Warning: Contains SPOILERS for X-Manhunt Omega #1 and the X-Manhunt event
Professor X
’s era of terror, cruelty, and deceit is finally over, as Marvel has just established the perfect excuse for his horrific past behaviors. While Xavier was seemingly beyond redemption, the Professor has been suffering from a genetic disorder that affects every mutant of his kind, and inevitably detrimentally warps their psychic minds. However, Charles is now free from his sickness and is leaving his villainous era in the past.
In X-Manhunt: Omega #1 – written by Murewa Ayodele and Gail Simone, with art by Gleb Melnikov, Federica Manciń, and Enid Balám –
Charles Xavier and his resurrected wife
, Lilandra, escape from Earth after Xavier receives a telepathic call for help from his daughter, Xandra.
The issue also dealt with tumor that has been developing inside Charles’s brain, which has gradually warped his emotions and mental clarity. Finally accepting this affliction, Xavier has Lilandra surgically remove the cancerous growth, so he can meet his daughter with a sound mind. With the tumor removed, Xavier awakens to just how far he has gone.
Marvel Reveals Charles Xavier’s Brain Tumor Is What Started His Villainous Downfall
X-Manhunt: Omega #1 – Written By Murewa Ayodele & Gail Simone; Art By Gleb Melnikov, Federica Manciń, & Enid Balám; Color By Brian Reber; Lettering By VC’s Travis Lanham
In Uncanny X-Men #8 – written by Gail Simone, with art by Javier Garrón – fans learned that Charles Xavier has been suffering from a growing brain tumor for an undisclosed period of time. However, while
Rogue’s X-Men
desperately tried to make the Professor accept this, Charles obstinately opposed the idea. It wasn’t until Lilandra’s resurrection in X-Force #9 – written by Geoffrey Thorne, with art by Marcus To – that she was able to convince Charles of the growing tumor in his head. At that moment, the Professor finally realized how warped he had become in the past few years.

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However, when Lilandra successfully removes the growth from Charle’s brain, there is a sudden change in the Professor’s behavior. His long-hardened expression melts into soft concern. His “ends justify the means” mentality fades into shame for his cruelty. And, for the first time since Krakoa’s founding, Charles is ready to let go of his militant ways and re-embrace his role as a father figure and teacher. As
Xavier returns to Earth
to give his X-Men a final goodbye, his words ring with the same loving gravitas that the X-Man has historically been known for.
Charles Xavier’s Affliction Impacts Others Of His Kind, Marvel’s “Avians”
A Shared Genetic Fault
What’s especially interesting about Charles’s brain tumor is that he isn’t the only mutant of his kind to have one. In Uncanny X-Men #8, it was established that Xavier belongs to a specific subgroup of telepathic mutants known as the “Avians.” Alongside mutants like Cassandra Nova and Scurvy, these Avian mutants also share a genetic predisposition to brain cancer. Uncanny X-Men #1 introduced Harvey X, another young Avian psychic, who died from his tumor in the same issue. This isn’t just
a Charles Xavier problem
, it’s a common struggle for all Avians.
While it’s difficult to say with absolute certainty, there is a significantly likely chance that this is the excuse for Xavier’s previous, horrific, militant behavior.
Now,
Charles Xavier is finally free
from the tumor that has plagued him. While it’s difficult to say with absolute certainty, there is a significantly likely chance that this is the excuse for Xavier’s previous, horrific, militant behavior. Charles’s actions have divided both the X-Men and X-Men readers, as we have all been left hurt and confused by the Professor’s betrayal of his ideals and dream. In truth, Professor X was never a true villain but, instead, a victim of a disease that inevitably drives Avians, like himself, toward cruel and short-sighted behavior.
X-Manhunt: Omega #1 is now available from Marvel Comics.